Design and system evaluation of a dual-panel portable PET (DP-PET)

Abstract Background Integrated whole-body PET/MR technology continues to mature and is now extensively used in clinical settings. However, due the special design architecture, integrated comes with a few inherent limitations. Firstly, lacks sensitivity resolution for focused organs. Secondly, broader access of has been significantly restricted its prohibitively high cost. The MR-compatible PET insert an independent removable scanner which can be placed within MRI bore. mobility configurability all existing prototypes remain limited. Methods An portable prototype, dual-panel (DP-PET), developed simultaneous imaging. Using SiPM, digital readout electronics, novel carbon fiber shielding, phase-change cooling, compatible battery power, DP-PET was designed achieve high-sensitivity high-resolution compatibility 3-T scanner. A GPU-based reconstruction method modeling (RM) reconstruction. We evaluated system performance on resolution, sensitivity, image quality, interference. Results initial results reveal that prototype worked as expected bore caused minimal compromise quality. measured show spatial ≤ 2.5 mm (parallel detector panels), maximum = 3.6% at center FOV, energy 12.43%. MR pulsing introduces less than 2% variation measurement results. Conclusions performed several studies begin characterize proposed DP-PET. showed well would cause little influence images. Derenzo phantom test could obtain high-quality images using